Structure of PDB 5e6s Chain B

Receptor sequence
>5e6sB (length=455) Species: 9606 (Homo sapiens) [Search protein sequence]
QECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSIRCDTRPQLLMRG
CAADDIMDPTSLAETQEDQKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYP
IDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTV
LPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLI
SGNLDAPEGGLDAMMQVAACPEEIGWRKVTRLLVFATDDGFHFAGDGKLG
AILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRM
VKTYEKLTEIIPKSAVGELSEDSSNVVQLIKNAYNKLSSRVFLDHNALPD
TLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQEQSF
VIRALGFTDIVTVQVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGY
IGKNC
3D structure
PDB5e6s Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
ChainB
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B S116 D119 D120 E325 S112 D115 D116 E321
BS02 CA B D151 N207 D209 P211 E212 D147 N203 D205 P207 E208
External links
PDB RCSB:5e6s, PDBe:5e6s, PDBj:5e6s
PDBsum5e6s
PubMed26936951
UniProtP05107|ITB2_HUMAN Integrin beta-2 (Gene Name=ITGB2)

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