Structure of PDB 5e1c Chain B

Receptor sequence
>5e1cB (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5e1c Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E380 D538 L539 E542 I54 K58 L68 V72 L75 E76 D231 L232 E235
BS02 5K8 B M343 T347 A350 E353 L387 F404 M421 G521 H524 L525 M39 T43 A46 E49 L83 F100 M117 G214 H217 L218
External links
PDB RCSB:5e1c, PDBe:5e1c, PDBj:5e1c
PDBsum5e1c
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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