Structure of PDB 5e19 Chain B

Receptor sequence
>5e19B (length=238) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5e19 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 D538 L539 E542 I54 K58 L68 V72 D228 L229 E232
BS02 5K7 B T347 A350 E353 L387 M421 I424 L525 T43 A46 E49 L83 M117 I120 L215
External links
PDB RCSB:5e19, PDBe:5e19, PDBj:5e19
PDBsum5e19
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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