Structure of PDB 5e15 Chain B

Receptor sequence
>5e15B (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKVVPLSDLLLEMLDAHRL
3D structure
PDB5e15 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 V376 D538 L539 E542 I54 K58 V72 D222 L223 E226
BS02 5KA B T347 A350 E353 L387 F404 L525 L540 T43 A46 E49 L83 F100 L212 L224
External links
PDB RCSB:5e15, PDBe:5e15, PDBj:5e15
PDBsum5e15
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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