Structure of PDB 5e14 Chain B

Receptor sequence
>5e14B (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMNVVPLSDLLLEMLDAHRL
3D structure
PDB5e14 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 L379 E380 D538 L539 E542 I54 K58 V72 L75 E76 D226 L227 E230
BS02 5KB B M343 T347 E353 L387 F404 M421 F425 M39 T43 E49 L83 F100 M117 F121
External links
PDB RCSB:5e14, PDBe:5e14, PDBj:5e14
PDBsum5e14
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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