Structure of PDB 5e0x Chain B

Receptor sequence
>5e0xB (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5e0x Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.014 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 V376 E380 D538 L539 E542 I50 K54 V68 E72 D220 L221 E224
BS02 5KD B E353 L387 G420 M421 I424 H524 L525 E45 L79 G112 M113 I116 H206 L207
External links
PDB RCSB:5e0x, PDBe:5e0x, PDBj:5e0x
PDBsum5e0x
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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