Structure of PDB 5e0w Chain B

Receptor sequence
>5e0wB (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSETRPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5e0w Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 Q375 V376 E380 D538 L539 E542 I51 K55 Q68 V69 E73 D220 L221 E224
BS02 5KE B E353 L387 F404 E419 G420 M421 I424 H524 L525 E46 L80 F97 E112 G113 M114 I117 H206 L207
External links
PDB RCSB:5e0w, PDBe:5e0w, PDBj:5e0w
PDBsum5e0w
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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