Structure of PDB 5dyj Chain B

Receptor sequence
>5dyjB (length=253) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
ISSETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLG
VGTDENYPLGTTTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEA
EQQASRELYFEAVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSP
PILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQMIVVD
IQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLD
VKL
3D structure
PDB5dyj Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.7: [myosin heavy-chain] kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B H742 H794 C796 C800 H186 H238 C240 C244
BS02 AMP B A587 E588 G589 K645 E713 L716 F720 D766 A36 E37 G38 K94 E157 L160 F164 D210
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5dyj, PDBe:5dyj, PDBj:5dyj
PDBsum5dyj
PubMed27211275
UniProtP42527|MHCKA_DICDI Myosin heavy chain kinase A (Gene Name=mhkA)

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