Structure of PDB 5dy8 Chain B

Receptor sequence
>5dy8B (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5dy8 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.031 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 Q375 V376 E380 D538 E542 I54 K58 L68 Q71 V72 E76 D224 E228
BS02 5K4 B L346 T347 A350 E353 L387 M421 L428 L525 L42 T43 A46 E49 L83 M112 L119 L211
External links
PDB RCSB:5dy8, PDBe:5dy8, PDBj:5dy8
PDBsum5dy8
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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