Structure of PDB 5dxm Chain B

Receptor sequence
>5dxmB (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAH
3D structure
PDB5dxm Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.37 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 D538 L539 E542 I54 K58 L68 V72 L75 D228 L229 E232
BS02 5J0 B L346 T347 A350 E353 M388 M421 L525 L42 T43 A46 E49 M84 M117 L215
External links
PDB RCSB:5dxm, PDBe:5dxm, PDBj:5dxm
PDBsum5dxm
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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