Structure of PDB 5dxk Chain B

Receptor sequence
>5dxkB (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5dxk Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.226 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E380 D538 L539 E542 I54 K58 L68 V72 L75 E76 D228 L229 E232
BS02 5J1 B L346 T347 A350 E353 M388 F404 M421 I424 L525 L42 T43 A46 E49 M84 F100 M117 I120 L215
External links
PDB RCSB:5dxk, PDBe:5dxk, PDBj:5dxk
PDBsum5dxk
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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