Structure of PDB 5dwj Chain B

Receptor sequence
>5dwjB (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTE
EKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5dwj Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 D538 L539 E542 M543 I53 K57 V71 D218 L219 E222 M223
BS02 5J2 B L346 T347 A350 E353 L387 L391 I424 H524 L525 L41 T42 A45 E48 L82 L86 I113 H204 L205 BindingDB: EC50=10.0nM
External links
PDB RCSB:5dwj, PDBe:5dwj, PDBj:5dwj
PDBsum5dwj
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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