Structure of PDB 5dwg Chain B

Receptor sequence
>5dwgB (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
LTADQMVSALLDAEPPILYSEYDSEASMMGLLTNLADRELVHMINWAKRV
PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ
GKGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYEEKDHIHR
VLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYS
MKCKLSDLLLEMLDAH
3D structure
PDB5dwg Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 L539 I44 K48 V62 L208
BS02 5G4 B L346 T347 A350 E353 L387 L391 M421 I424 G521 L525 L32 T33 A36 E39 L73 L77 M104 I107 G194 L198
External links
PDB RCSB:5dwg, PDBe:5dwg, PDBj:5dwg
PDBsum5dwg
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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