Structure of PDB 5dwe Chain B

Receptor sequence
>5dweB (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
EKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5dwe Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 D538 L539 E542 I53 K57 L67 V71 E75 D218 L219 E222
BS02 5G5 B M343 L346 T347 A350 E353 L387 F404 M421 L525 M38 L41 T42 A45 E48 L82 F99 M111 L205 BindingDB: EC50=1.000000nM
External links
PDB RCSB:5dwe, PDBe:5dwe, PDBj:5dwe
PDBsum5dwe
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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