Structure of PDB 5dwb Chain B

Receptor sequence
>5dwbB (length=278) Species: 53501 (Thalassovita gelatinovora) [Search protein sequence]
MRLDLDFGRGLVAHVMLDNVSEEQYQQISDYFVPLVNKPKLKSRDAIGQA
FVMATEVCPDANPSDLWHHVLYRIYIREKIGTDPSQSWVRTSGEAFEVAL
VERYNPVLARHGIRLTALFKGQKGLALTRMGVADRVGSRKVDVMIEKQGG
GRSPDAEGFGVVGGIHAKVSLAERVSDDIPASRIMMGEGLLSVLSTLDVK
SFPPPHGDLVNRGELGTPDRPSDKRNYIEGHGDFSACFSYNLRTSPSNAT
TPSGRHIYVSGFSGQDDEFTDYLVAQLA
3D structure
PDB5dwb Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Y72 V89 R90 R139 K168 V169 S170 R174 K200 F202 Y72 V89 R90 R139 K168 V169 S170 R174 K200 F202
BS02 dna B K42 R44 T82 D83 Q86 S87 V89 R90 F119 K120 E173 F202 K224 K42 R44 T82 D83 Q86 S87 V89 R90 F119 K120 E173 F202 K224
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:5dwb, PDBe:5dwb, PDBj:5dwb
PDBsum5dwb
PubMed28039325
UniProtQ9KHV6|T2A1_THAGE Type II restriction enzyme AgeI (Gene Name=ageIR)

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