Structure of PDB 5dvv Chain B

Receptor sequence
>5dvvB (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
SLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWAKRVPGF
VDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDGMVEIF
DMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTDHIHRVLDKITDTLI
HLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLS
DLLLEMLDAH
3D structure
PDB5dvv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.505 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 V376 D538 E542 I41 V59 D201 E205
BS02 5G6 B M343 L346 T347 A350 E353 L387 G521 L525 M26 L29 T30 A33 E36 L70 G184 L188 BindingDB: EC50=3.0nM
External links
PDB RCSB:5dvv, PDBe:5dvv, PDBj:5dvv
PDBsum5dvv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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