Structure of PDB 5dvs Chain B

Receptor sequence
>5dvsB (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTKDH
IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEH
LYSMKCKNVPLSDLLLEMLDAHR
3D structure
PDB5dvs Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 L379 L539 E542 I51 K55 V69 L72 L214 E217
BS02 5G7 B T347 A350 E353 L387 M421 I424 G521 L525 T40 A43 E46 L80 M108 I111 G197 L201 BindingDB: EC50=7.0nM
External links
PDB RCSB:5dvs, PDBe:5dvs, PDBj:5dvs
PDBsum5dvs
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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