Structure of PDB 5due Chain B

Receptor sequence
>5dueB (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5due Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E542 M543 I55 K59 L69 V73 E235 M236
BS02 5FY B L346 T347 E353 M388 F404 V418 M421 G521 H524 L525 M528 L43 T44 E50 M85 F101 V115 M118 G214 H217 L218 M221 BindingDB: EC50=9.2nM
External links
PDB RCSB:5due, PDBe:5due, PDBj:5due
PDBsum5due
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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