Structure of PDB 5dtv Chain B

Receptor sequence
>5dtvB (length=238) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dtv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.295 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 D538 L539 E542 M543 I54 K58 L68 V72 L75 D228 L229 E232 M233
BS02 5FS B L346 T347 A350 E353 L387 M421 F425 L525 L540 L42 T43 A46 E49 L83 M117 F121 L215 L230
External links
PDB RCSB:5dtv, PDBe:5dtv, PDBj:5dtv
PDBsum5dtv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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