Structure of PDB 5drm Chain B

Receptor sequence
>5drmB (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFLSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKVVPLSDLLLEMLDAHR
3D structure
PDB5drm Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.241 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 D538 L539 E542 I49 K53 L63 V67 E71 D225 L226 E229
BS02 5ET B L346 E353 L387 L525 L37 E44 L78 L215 BindingDB: EC50=2180nM
External links
PDB RCSB:5drm, PDBe:5drm, PDBj:5drm
PDBsum5drm
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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