Structure of PDB 5drj Chain B

Receptor sequence
>5drjB (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5drj Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 Q375 V376 L379 E380 D538 L539 E542 M543 I54 K58 L68 Q71 V72 L75 E76 D231 L232 E235 M236
BS02 5EU B L346 E353 G420 M421 I424 G521 H524 L42 E49 G116 M117 I120 G214 H217 BindingDB: EC50=101nM
External links
PDB RCSB:5drj, PDBe:5drj, PDBj:5drj
PDBsum5drj
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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