Structure of PDB 5dp0 Chain B

Receptor sequence
>5dp0B (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dp0 Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.382 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 V376 D538 L539 E542 M543 I54 K58 L68 V72 D222 L223 E226 M227
BS02 5ES B M343 L346 T347 A350 E353 M421 F425 L525 M39 L42 T43 A46 E49 M111 F115 L209
External links
PDB RCSB:5dp0, PDBe:5dp0, PDBj:5dp0
PDBsum5dp0
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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