Structure of PDB 5dnx Chain B

Receptor sequence
>5dnxB (length=176) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MRRTTKETDIIVEIGKKGEIKTNDLILDHMLTAFAFYLGKDMRITATYDL
RHHLWEDIGITLGEALRENLPEKFTRFGNAIMPMDDALVLVSVDISNRPY
ANVDVNIKDAEEGFAVSLLKEFVWGLARGLRATIHIKQLSGENAHHIVEA
AFKGLGMALRVATKESERVESTKGVL
3D structure
PDB5dnx Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
ChainB
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5LD B H29 M84 H145 H146 E149 H29 M84 H145 H146 E149
BS02 MN B H29 H145 E149 H29 H145 E149
BS03 5LD B R76 R98 S171 K173 R76 R98 S171 K173
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
GO:0016829 lyase activity
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5dnx, PDBe:5dnx, PDBj:5dnx
PDBsum5dnx
PubMed27717128
UniProtP58880|HIS7_PYRFU Imidazoleglycerol-phosphate dehydratase (Gene Name=hisB)

[Back to BioLiP]