Structure of PDB 5dmf Chain B

Receptor sequence
>5dmfB (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5dmf Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E380 E542 I53 K57 L67 V71 L74 E75 E227
BS02 5DG B M343 T347 A350 E353 L387 M421 G521 H524 M38 T42 A45 E48 L82 M116 G206 H209
External links
PDB RCSB:5dmf, PDBe:5dmf, PDBj:5dmf
PDBsum5dmf
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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