Structure of PDB 5dlr Chain B

Receptor sequence
>5dlrB (length=240) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
3D structure
PDB5dlr Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 Q375 V376 E380 L539 E542 I54 K58 L68 Q71 V72 E76 L229 E232
BS02 5DJ B T347 A350 E353 L387 M421 I424 L525 T43 A46 E49 L83 M115 I118 L215
External links
PDB RCSB:5dlr, PDBe:5dlr, PDBj:5dlr
PDBsum5dlr
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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