Structure of PDB 5dks Chain B

Receptor sequence
>5dksB (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKPLSDLLLEMLDAHR
3D structure
PDB5dks Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 D538 L539 E542 M543 I52 K56 V70 D217 L218 E221 M222
BS02 5C6 B M342 M343 L346 T347 A350 E353 L387 F404 M421 F425 G521 H524 L525 M36 M37 L40 T41 A44 E47 L81 F98 M112 F116 G205 H208 L209
External links
PDB RCSB:5dks, PDBe:5dks, PDBj:5dks
PDBsum5dks
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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