Structure of PDB 5dke Chain B

Receptor sequence
>5dkeB (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMVVPLSDLLLEMLDAHRLHAPTS
3D structure
PDB5dke Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 V376 L379 D538 L539 E542 M543 I54 K58 V72 L75 D219 L220 E223 M224
BS02 5C8 B M343 L346 A350 E353 L387 F404 E419 M421 I424 G521 H524 L525 M39 L42 A46 E49 L83 F100 E115 M117 I120 G206 H209 L210
External links
PDB RCSB:5dke, PDBe:5dke, PDBj:5dke
PDBsum5dke
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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