Structure of PDB 5dk3 Chain B

Receptor sequence
>5dk3B (length=441) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQLVQSGVEVKKPGASVKVSCKASGYTFTNYYMYWVRQAPGQGLEWMGG
INPSNGGTNFNEKFKNRVTLTTDSSTTTAYMELKSLQFDDTAVYYCARRD
YRFDMGFDYWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVK
DYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKT
YTCNVDHKPSNTKVDKRVESKYGPPCPPCEFLGGPSVFLFPPKPKDTLMI
SRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVV
SVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPP
SQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGS
FFLYSRLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS
3D structure
PDB5dk3 Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab.
ChainB
Resolution2.28 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA B F241 F243 F238 F240
BS02 FUC B N276 S324 N273 S321
BS03 GLC B A378 T393 P395 A375 T390 P392
BS04 FRU B K392 T393 K389 T390
BS05 GLC B Q362 R409 Q359 R406
External links