Structure of PDB 5die Chain B

Receptor sequence
>5dieB (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVPLSDLLLEMLDAHR
3D structure
PDB5die Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 V376 E380 D538 L539 E542 I52 K56 V70 E74 D225 L226 E229
BS02 5CJ B M343 L346 L349 A350 E353 L387 M388 M421 H524 M37 L40 L43 A44 E47 L81 M82 M115 H212
External links
PDB RCSB:5die, PDBe:5die, PDBj:5die
PDBsum5die
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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