Structure of PDB 5d92 Chain B

Receptor sequence

>5d92B (length=342) Species: 224325,288705

MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDY
LIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIE
KYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIGSGSLNKYARGLFAA
IFLPIARLLADWGVSPDAVTVVGTLGVMAGALIFYPMGQLFWGTVVITVF
VFSDIIDGLMARLLFREGPWGAFLDSYLDRVGDSSVFTGIVIWFFLGGAN
PTIAILALICLVLSSLVSYSKARAEGLGLTANVGIAERSERLVVVLVATG
LVGLGIPSWVLLVVLIVLAIASVVTIFQRVLTVREQAKAWTA

3D structure

• PDB: 5d92 Structural basis for phosphatidylinositol-phosphate biosynthesis.
• Chain: B
• Resolution: 3.62 Å

Enzymatic activity

• Enzyme Commision number:
  2.7.8.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	B	D66 D87 D91	D204 D225 D229
BS02	MG	B	D66 D69 G70 D87	D204 D207 G208 D225
BS03	58A	B	S-1 G0 D29 T60 V63 F64 D66 I67 D69 G70 A73 R74 E79 G83 A84 D87 R150 S151 V155	S137 G138 D167 T198 V201 F202 D204 I205 D207 G208 A211 R212 E217 G221 A222 D225 R288 S289 V293

Gene Ontology

Molecular Function

• GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Biological Process

• GO:0008654 phospholipid biosynthetic process

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:5d92, PDBe:5d92, PDBj:5d92
• PDBsum: 5d92
• PubMed: 26510127
• UniProt: A9WSF5;
  O27985