Structure of PDB 5d8l Chain B

Receptor sequence
>5d8lB (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKH
NNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLE
NIKRKV
3D structure
PDB5d8l Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors.
ChainB
Resolution2.069 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B F10 K54 H55 S60 R63 Q64 Y68 R109 F5 K49 H50 S55 R58 Q59 Y63 R104
BS02 dna B K54 R63 N66 R71 K72 K49 R58 N61 R66 K67
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5d8l, PDBe:5d8l, PDBj:5d8l
PDBsum5d8l
PubMed26727490
UniProtQ03933|HSF2_HUMAN Heat shock factor protein 2 (Gene Name=HSF2)

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