Structure of PDB 5czs Chain B

Receptor sequence
>5czsB (length=344) Species: 122586 (Neisseria meningitidis MC58) [Search protein sequence]
HYPTDDIKIKEVKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRD
KRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFAKPRVG
WKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYY
ADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAA
SHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQL
RAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVES
HLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR
3D structure
PDB5czs Structure of Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu98Ala variant at 2.42 Angstroms resolution
ChainB
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B C63 H270 E304 D324 C60 H265 E299 D319
BS02 PEP B R94 Y96 K188 R236 H270 R91 Y93 K183 R231 H265
BS03 PHE B Q153 L181 S182 F211 S213 Q148 L176 S177 F206 S208
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5czs, PDBe:5czs, PDBj:5czs
PDBsum5czs
PubMed
UniProtQ9K169

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