Structure of PDB 5cwe Chain B

Receptor sequence
>5cweB (length=393) Species: 227882 (Streptomyces avermitilis MA-4680 = NBRC 14893) [Search protein sequence]
MGNVIDLGEYGARFTEDPYPVYAELRERGPVHWVRTPPPEAFEGWLVVGH
EEARAALADPRLSKDGTKKGLTSLDVELMGPYLLVVDPPEHTRLRSLVAR
AFTMRRVEALRPRIQEITDGLLDEMLPRGRADLVDSFAYPLPITVICELL
GVPDIDRVTFRALSNEIVAPTGGDAELAAYERLAAYLDELIDDKRSTAPA
DDLLGDLIRTRAEDDDRLSGEELRAMAFILLVAGHETTVNLITNGVHTLL
THPDQLAALRADMTLLDGAVEEVLRFEGPVETATYRYAAESMEIGGTAIA
EGDPVMIGLDAAGRDPARHPDPHVFDIHRAPQGHLAFGHGIHYCLGAPLA
RLEARVALRSLLERCPDLALDGPPGARPPGMLIRGVRRLPVRW
3D structure
PDB5cwe Structure of CYP107L2 from Streptomyces avermitilis with lauric acid
ChainB
Resolution2.39 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A169 A233 E236 T237 T238 V280 C344 L345 G346 E353 I383
Catalytic site (residue number reindexed from 1) A169 A233 E236 T237 T238 V280 C344 L345 G346 E353 I383
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B L83 H91 R95 A233 G234 T237 T238 T284 R286 A336 F337 H342 C344 G346 A350 L83 H91 R95 A233 G234 T237 T238 T284 R286 A336 F337 H342 C344 G346 A350
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

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Molecular Function
External links
PDB RCSB:5cwe, PDBe:5cwe, PDBj:5cwe
PDBsum5cwe
PubMed
UniProtQ82LM3

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