Structure of PDB 5cmk Chain B

Receptor sequence
>5cmkB (length=253) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTY
EIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLTITYVREKVID
FSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSK
ISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTSDYALLMESTTIEFVTQR
NCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKW
WRG
3D structure
PDB5cmk Structural basis of kainate subtype glutamate receptor desensitization.
ChainB
Resolution1.801 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LY5 B Y61 P89 T91 R96 S142 T143 E191 Y217 Y60 P88 T90 R95 S141 T142 E190 Y216 MOAD: ic50=30nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5cmk, PDBe:5cmk, PDBj:5cmk
PDBsum5cmk
PubMed27580033
UniProtP42260|GRIK2_RAT Glutamate receptor ionotropic, kainate 2 (Gene Name=Grik2)

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