Structure of PDB 5cmb Chain B

Receptor sequence
>5cmbB (length=255) Species: 27923 (Mnemiopsis leidyi) [Search protein sequence]
GSKNLIGRHLRLGSVEEQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLG
FTYEYIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKS
AIDYSFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSKHPETLL
KTHRDSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDC
DVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSS
GNSVC
3D structure
PDB5cmb Molecular lock regulates binding of glycine to a primitive NMDA receptor.
ChainB
Resolution1.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG B D110 E213 D110 E213
BS02 GLY B F63 D91 L92 S93 R98 K144 H145 E188 F63 D91 L92 S93 R98 K144 H145 E188 MOAD: Kd=28.3nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0046872 metal ion binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5cmb, PDBe:5cmb, PDBj:5cmb
PDBsum5cmb
PubMed27791085
UniProtA0A0R4I973

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