Structure of PDB 5cd1 Chain B

Receptor sequence
>5cd1B (length=321) Species: 9606 (Homo sapiens) [Search protein sequence]
HRIRDGDFVVLKREDVFKAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFE
VTSGGSLQPKTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMY
YAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMG
GFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSY
IQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVA
PSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHP
KLLMSGGGGYLLSGFTVAMDN
3D structure
PDB5cd1 Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
ChainB
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B R415 V420 L423 R273 V278 L281
BS02 rna B V33 K150 K153 R175 E176 P177 K179 H182 V237 L444 V16 K78 K81 R103 E104 P105 K107 H110 V165 L302
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0031515 tRNA (m1A) methyltransferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5cd1, PDBe:5cd1, PDBj:5cd1
PDBsum5cd1
PubMed26470919
UniProtQ9UJA5|TRM6_HUMAN tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (Gene Name=TRMT6)

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