Structure of PDB 5c9h Chain B

Receptor sequence
>5c9hB (length=225) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
QYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYLKEYQSKNFSCQEERDLF
LEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKNLFNSLYDTEIS
YKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDY
ICFMDVFDVEWFVDLKNQKRKYISDKRKILGDLIVFIINKIVIPVLRYNF
YITEKEGSQIFYYRKPIWKLVSKLT
3D structure
PDB5c9h Structural basis of template-boundary definition in Tetrahymena telomerase.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B H234 G236 R237 F242 K243 S244 R473 H17 G19 R20 F25 K26 S27 R197
BS02 rna B M235 R237 E238 K328 L333 Y337 Q338 M18 R20 E21 K71 L76 Y80 Q81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003964 RNA-directed DNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:5c9h, PDBe:5c9h, PDBj:5c9h
PDBsum5c9h
PubMed26436828
UniProtO77448|TERT_TETTS Telomerase reverse transcriptase (Gene Name=TERT)

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