Structure of PDB 5c5v Chain B

Receptor sequence
>5c5vB (length=342) Species: 185431 (Trypanosoma brucei brucei TREU927) [Search protein sequence]
TQPMIKKIMSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKA
EINAIDGHVTFEKFWAWWCSHPVHSRTKCFSMVSADFSMPYHQQQLVVHE
KGEMYTPSYRVLYFFRDLETGRERQVSPWHDIPLYVRDLVRTKPEATPMN
RYNFICEIPKWTRAKFEIATGESFNPIKQDIKNGVPRFYKHGDMMWNYGA
FPQTWESTEVLFEAGVTGDNDPVDAVEIGMTQFKVGQVSAVKVLGVLGMI
DEGKMDWKVVCISHNDPICRFMKDIHDVPKFLPGCLDAIREWFRVYKICQ
GGEASHFAFDGEFKDKEYAMKVIDESHNMWHNLLKVNKRGEL
3D structure
PDB5c5v Structural and Functional Highlights of Vacuolar Soluble Protein 1 from Pathogen Trypanosoma brucei brucei
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2PN B K237 R259 Y270 D296 D328 Y368 K369 K165 R187 Y198 D224 D256 Y296 K297
BS02 MG B D291 D296 D328 D219 D224 D256
BS03 MG B D323 D328 D251 D256
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphate phosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5c5v, PDBe:5c5v, PDBj:5c5v
PDBsum5c5v
PubMed26494625
UniProtQ384W5

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