Structure of PDB 5brm Chain B

Receptor sequence
>5brmB (length=158) Species: 9606 (Homo sapiens) [Search protein sequence]
DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSVPFPKNFMSVAKTILKR
LFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPL
QELIEKLG
3D structure
PDB5brm Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
ChainB
Resolution2.651 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B P91 R92 Y93 E94 Y95 H96 K153 R154 R157 Y163 F167 M171 R199 E200 L207 K210 P40 R41 Y42 E43 Y44 H45 K99 R100 R103 Y109 F113 M117 R145 E146 L153 K156
BS02 peptide B N66 N69 Y72 D116 L126 D127 N15 N18 Y21 D65 L75 D76
BS03 ZN B C79 C84 H161 H166 C28 C33 H107 H112
External links
PDB RCSB:5brm, PDBe:5brm, PDBj:5brm
PDBsum5brm
PubMed26108669
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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