Structure of PDB 5b55 Chain B

Receptor sequence
>5b55B (length=333) Species: 190304 (Fusobacterium nucleatum subsp. nucleatum ATCC 25586) [Search protein sequence]
QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFY
TLKKAYEKNEIKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSE
ERKSLIRSFGAKIILVSRKEGGFLGSIEKTKEFAKNNPDTYLPSQFSNLY
NSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGTGGTVMGIGKRIKENFSN
AKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLDNVVSVDD
GDAIVMAQKLAKCGLGVGISSGANFIGALMLQNKLGKDSVIVTVFPDDNK
KYLSTDLMREEKVKEDFLSKDITLKEIKNVLRV
3D structure
PDB5b55 Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen sulfide-producing oral pathogen,Fusobacterium nucleatum.
ChainB
Resolution2.14 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K46 S272
Catalytic site (residue number reindexed from 1) K44 S270
Enzyme Commision number 2.5.1.47: cysteine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B K46 N76 G184 T185 G186 T188 S272 D299 K44 N74 G182 T183 G184 T186 S270 D297
BS02 0JO B K46 T73 S74 N76 T77 Q147 G182 V183 G184 T185 G186 T188 G229 I230 S272 P298 D299 K44 T71 S72 N74 T75 Q145 G180 V181 G182 T183 G184 T186 G227 I228 S270 P296 D297
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006534 cysteine metabolic process
GO:0006535 cysteine biosynthetic process from serine
GO:0009069 serine family amino acid metabolic process
GO:0044272 sulfur compound biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5b55, PDBe:5b55, PDBj:5b55
PDBsum5b55
PubMed29343611
UniProtQ8REP3

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