Structure of PDB 5b4c Chain B

Receptor sequence
>5b4cB (length=231) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
SVLFISDLNLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDG
MDAFQRSIAQSLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPS
VIDLYGEPVLLMHGDSLCTRDEAYMRLRRWLRNPLTLWVLRHLPLATRHK
LARKLRKESDIIDVTPEEVPRVMRGHGVRTLIHGHTHRPAEHPLDIDGQP
ARRIVLGDWDRQGWALEIDANGHRQAPFPLL
3D structure
PDB5b4c Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
ChainB
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.54: UDP-2,3-diacylglucosamine diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D41 N79 H114 H195 D40 N78 H113 H185
Gene Ontology
Molecular Function
GO:0008758 UDP-2,3-diacylglucosamine hydrolase activity
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
GO:0051861 glycolipid binding
Biological Process
GO:0009245 lipid A biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0019897 extrinsic component of plasma membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5b4c, PDBe:5b4c, PDBj:5b4c
PDBsum5b4c
PubMed27609419
UniProtQ9I2V0|LPXH_PSEAE UDP-2,3-diacylglucosamine hydrolase (Gene Name=lpxH)

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