Structure of PDB 5azt Chain B

Receptor sequence
>5aztB (length=251) Species: 9606 (Homo sapiens) [Search protein sequence]
KSLAKRIYEAYLKNFNMNKVKARVILSGKASNPPFVIHDMETLCMAEKTL
KEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYE
AIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKF
NALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSN
HPDDIFLLPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYR
D
3D structure
PDB5azt 17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
ChainB
Resolution3.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4M5 B L247 E251 C275 C276 T279 S280 Y314 V332 H440 L43 E47 C60 C61 T64 S65 Y99 V117 H225
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5azt, PDBe:5azt, PDBj:5azt
PDBsum5azt
PubMed27337155
UniProtQ07869|PPARA_HUMAN Peroxisome proliferator-activated receptor alpha (Gene Name=PPARA)

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