Structure of PDB 5aqc Chain B

Receptor sequence
>5aqcB (length=181) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
AQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVH
LLVSALGREFSRIDAKTSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAM
TRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVISDVW
LSNLLAWLTRRASATDVSKRLDLAVRLLIGD
3D structure
PDB5aqc Kstr, Transcriptional Repressor of Cholesterol Degradation in Mycobacterium Tuberculosis, Bound to the Cholesterol Coenzyme a Derivative, (25S)-3- Oxocholest-4-En-26-Oyl-Coa.
ChainB
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5JB B M125 Y139 I157 S182 W185 M90 Y104 I122 S147 W150
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5aqc, PDBe:5aqc, PDBj:5aqc
PDBsum5aqc
PubMed
UniProtP96856|KSTR_MYCTU HTH-type transcriptional repressor KstR (Gene Name=kstR)

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