Structure of PDB 5aip Chain B

Receptor sequence
>5aipB (length=132) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence]
SINIGLIQAREALMTQFRPILNQANITDQQWRIIRLLAENGTLDFQDLAN
QACILRPSLTGILTRLEKAGLVVRLKPRVFLKLTAEGEKLYEEIGEEVDE
RYDAIEEVLGREKMLLLKDLLAELAKIEDALN
3D structure
PDB5aip Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4HP B M22 F25 L29 D36 W39 R43 Y115 M14 F17 L21 D28 W31 R35 Y102 MOAD: Kd=1.5mM
PDBbind-CN: -logKd/Ki=2.82,Kd=1.5mM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006950 response to stress
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5aip, PDBe:5aip, PDBj:5aip
PDBsum5aip
PubMed27105075
UniProtQ7DD70

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