Structure of PDB 5ahm Chain B

Receptor sequence
>5ahmB (length=347) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MLRISQEALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMD
TVTEARLAIAMAQEGGIGIIHKNMGIEQQAAEVRKVKKHETTYPLASKDE
QGRLRVGAAVGTGADTGERVAALVAAGVDVVVVDTAHGHSKGVIERVRWV
KQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIVAGVG
VPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMF
AGTEEAPGEIELFQGRSYKSYRGMGPEGIEGRVPYKGALSAIVHQLMGGL
RAAMGYTGSADIQQMRTQPQFVRITGAGMAESHVHDVQITKEAPNYR
3D structure
PDB5ahm Crystallographic Studies of Two Variants of Pseudomonas Aeruginosa Impdh with Impaired Allosteric Regulation
ChainB
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP B M49 G301 S302 I303 C304 D337 M359 G360 S361 Y384 G386 M387 G388 E417 M49 G188 S189 I190 C191 D224 M246 G247 S248 Y271 G273 M274 G275 E277
BS02 PO4 B G329 G331 G216 G218
BS03 PO4 B D212 E213 R218 D99 E100 R105
BS04 PO4 B Q63 H89 Y206 Q63 H89 Y93
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5ahm, PDBe:5ahm, PDBj:5ahm
PDBsum5ahm
PubMed26327379
UniProtQ9HXM5

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