Structure of PDB 5ah2 Chain B

Receptor sequence
>5ah2B (length=377) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
TDLKFRVVREDFADAVAWVARSLPTPTIPVLAGVLLTGTDEGLTISGFDY
EVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTC
GSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRLPML
TGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEA
AKAGTDGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQL
LPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADD
VGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAV
LRPAGGSGPFPAAKTDYVYLLMPVRLP
3D structure
PDB5ah2 Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
ChainB
Resolution2.129 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R181 F182 R183 L262 M391 P392 V393 R394 R169 F170 R171 L250 M372 P373 V374 R375
BS02 peptide B I37 D123 I28 D114
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0046677 response to antibiotic
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ah2, PDBe:5ah2, PDBj:5ah2
PDBsum5ah2
PubMed26045430
UniProtA0QND6|DPO3B_MYCS2 Beta sliding clamp (Gene Name=dnaN)

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