Structure of PDB 5ac4 Chain B

Receptor sequence
>5ac4B (length=625) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
VRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGEEGHYQLT
YRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVA
SAKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEA
YAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDL
IDGMFATLSKLKTRKVNIGMDQAHLVGLGRYLILNGVVDRSLLMCQHLER
VLDIADKYGFHCQMWSDMFFKLMSADGQYDRDVEIPEETRVYLDRLKDRV
TLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAGGAWKWIGFTPHNHFSRL
VAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIWAELSYRNDL
DGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDILC
PILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSK
VDVGRRIRQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENK
VFGLDTVDIRMGGLLQRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFY
ADKDFAATTANQWHTIATASTIYTT
3D structure
PDB5ac4 A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
ChainB
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NGA B R94 D222 Q223 W266 W306 Y308 W339 W373 D375 R93 D221 Q222 W265 W305 Y307 W338 W372 D374
Gene Ontology
Molecular Function
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0015929 hexosaminidase activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5ac4, PDBe:5ac4, PDBj:5ac4
PDBsum5ac4
PubMed26491009
UniProtA0A0H2US73

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