Structure of PDB 5a72 Chain B

Receptor sequence
>5a72B (length=158) Species: 3077 (Chlorella vulgaris) [Search protein sequence]
NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQH
FILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLNLKRAQ
AKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECL
KKLGHVVS
3D structure
PDB5a72 Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
ChainB
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A22 D23
Catalytic site (residue number reindexed from 1) A17 D18
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R33 D35 Y36 L37 Q41 R71 R73 N74 G84 K142 R28 D30 Y31 L32 Q36 R66 R68 N69 G79 K137 PDBbind-CN: Kd=53.3nM
BS02 dna B A22 D23 C25 Q29 R43 F49 Q50 S51 R73 M77 T139 D140 G141 R144 T145 I146 A17 D18 C20 Q24 R38 F44 Q45 S46 R68 M72 T134 D135 G136 R139 T140 I141 PDBbind-CN: Kd=53.3nM
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
Cellular Component
GO:0009507 chloroplast

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Biological Process
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Cellular Component
External links
PDB RCSB:5a72, PDBe:5a72, PDBj:5a72
PDBsum5a72
PubMed26363068
UniProtP56347|DNE1_CHLVU DNA endonuclease I-CvuI

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