Structure of PDB 4zyr Chain B

Receptor sequence
>4zyrB (length=385) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
NTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTWIIFAAISLF
SLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILV
GSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCA
SIVGIMFTINNQFVFWLGSGCALILAVLLFFAKAFSLKLALELFRQPKLW
FLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFWYVTTMGELLNA
SIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHM
FEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMY
ESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSL
3D structure
PDB4zyr Structure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site.
ChainB
Resolution3.312 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9PG B F27 R144 C148 W151 E269 N272 F22 R139 C143 W146 E246 N249
Gene Ontology
Molecular Function
GO:0005351 carbohydrate:proton symporter activity
GO:0005515 protein binding
GO:0015293 symporter activity
GO:0015528 lactose:proton symporter activity
GO:0022857 transmembrane transporter activity
GO:0030395 lactose binding
Biological Process
GO:0008643 carbohydrate transport
GO:0015767 lactose transport
GO:0034219 carbohydrate transmembrane transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:4zyr, PDBe:4zyr, PDBj:4zyr
PDBsum4zyr
PubMed26157133
UniProtP02920|LACY_ECOLI Lactose permease (Gene Name=lacY)

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