Structure of PDB 4zvr Chain B

Receptor sequence
>4zvrB (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
YKIPVEADFLFAYSTVPGYVSYRVPGRGSWFVQALCSILEEHGKDLEIMQ
ILTRVNDRVARHFESDSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB4zvr Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S231 Y232 R233 P235 S275 D276 S21 Y22 R23 P25 S65 D66
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4zvr, PDBe:4zvr, PDBj:4zvr
PDBsum4zvr
PubMed27032039
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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